Available Innovations

text_image
text_background
x
BIOTECH & LIFE SCIENCES
DIGITAL
PHYSICAL SCIENCES
AGRICULTURE & FOODTECH

Local Anaesthetic Implants

Research shows that three-day regional infusions of local anaesthetics reduce pain and improve recovery following major abdominal surgery. We have developed an implant which can release an analgesic drug locally to the surgical site for 3 days following abdominal surgery, after which it can be removed.

Contact:

Kent Lee

PachyMatrix

Researchers from the University of Auckland Department of Ophthalmology have developed a topical eye formula to treat and reverse the symptoms of Keratoconus without the need for invasive ocular surgery. Preclinical ex-vivo large animal studies have shown efficacy of the formulation in reprogramming stromal keratocyes to deposit new non-scarring collagen. This technology may have applicability for any ocular disorder involving thinning or misshaping of the cornea such as myopia.

Contact:

Kent Lee

Real-time 3D Heart Mapping for Atrial Fibrillation

A heart mapping system that will improve cardiac ablation procedures in patients with persistent or permanent atrial fibrillation. By enabling real time 3D mapping of electrical activity in the heart, the technology provides a unique way of constructing maps that will reduce treatment times and improve outcomes of ablation procedures.

Contact:

Kent Lee

Pressure vessel for sensor recalibration

A pressure measuring system is proposed where the drift of a pressure sensor can be quantified by detecting changes in compliance of a pressure vessel which encloses the sensor.

Contact:

Kent Lee

Gap19 Peptide for Age Related Macular Degeneration

XentryGap19 (XG19) is an intracellularly acting peptide that blocks gap junction hemichannel function. It utilises a specific cell receptor for uptake, which is highly expressed in tissues with poor blood flow (resulting in ischaemia and hypoxia) while not being expressed in circulating blood cells. Thus, XG19 is specifically delivered into affected tissues reducing the dose required and thus any potential side effects. The targeted and efficient uptake of XG19 into ischaemic and hypoxic cells blocks uncontrolled Connexin43 hemichannels opening (whilst maintaining gap junction communication required for normal cell communication) and spares affected cells from dying thus enabling repair of the leaky vasculature and restoration of normal blood flow

Contact:

Kent Lee

CSF-1R Inhibitor Program

We have developed a novel series of highly potent and selective CSF-1R inhibitors that are currently at lead stage. We have identified a unique scaffold consisting of a tricyclic heterocyclic compound with improved selectively over competitors’ programmes.

Contact:

Sandhya Badrinarayanan

Erp44/Adiponectin

A novel cell penetrating peptide derived from the ERp44 binding region of adiponectin and Immunoglobulin (IgM) was synthesised and conjugated with cell penetrating sequences. These peptides were designed to modulate in vivo oligomeric composition and secretion of the insulin-sensitizing high-molecular-weight (HMW) isoform of adiponectin. Targeting ERp44-adiponectin interactions with short peptides represents an effective method to treat obesity related metabolic disorders.

Contact:

Sandhya Badrinarayanan

HSMKI FGFR

Many cancer types demonstrate amplification of FGFR1-3. Systemic administration of selective FGFR1-3 inhibitors is associated with dose-limiting toxicities derived from on-target inhibition in normal tissues. These toxicities are thought to compromise efficacy in cancer patients with amplified FGFR-signalling. To date, no FGFR-selective inhibitors have gained FDA approval. We have invented a class of hypoxia-activated FGFR inhibitors with potential to selectively target tumour FGFR-signalling while sparing systemic toxicity. Development of a lead prodrug candidate holds the promise to improve the treatment of FGFR-amplified cancers.

Contact:

Sandhya Badrinarayanan

pH CORMs

We have developed a novel ruthenium-based CORMs that are pH responsive designed for tissue selectivity that is triggered to release CO when it encounters a slightly acidic environment. Hypoxic tissues are generally acidic; therefore relevant to ischemia and myocardial infarction, solid tumours, organ transplants.

Contact:

Sandhya Badrinarayanan

 

Click here to view a complete list of Biomedical and MedTech Innovations

 

 

BlokIDE - 3TwoOne

BlokIDE is set of software tools that allow software to be directly developed using block diagrams, permits detailed simulations to be run, and then automatically delivers production code free from human errors: line-by-line coding is not needed.

Contact:

Joe Rouse

Organ Emulation On FPGA

Emulated organs built from sophisticated software and Field-Programmable Gate Arrays, mimicking human organ behaviour from the cell level, including disease states, with unprecedented accuracy - personalized to individuals - in real time

Contact:

Joe Rouse

Certificate Revocation Guard

In the Public Key infrastructure (PKI) model, digital certificates play a vital role in securing online communication.  Communicating parties exchange and validate these certificates and the validation fails if a certificate has been revoked.  Certificate Revocation Guard (CRG) efficiently checks certificate revocation while minimising bandwidth, latency and storage overheads

Contact:

Joe Rouse

Secure Cloud Encryption

An encrypted cloud storage system that allows to users to perform advanced search operations on outsourced data without the need for cloud service providers to access the decrypted data and/or keying material. The novel obfusaction methods also prevent side-channel attacks by hiding the frequency, size, and timing patterns for file access. 

Contact:

Joe Rouse

Process Control of an industrial plant (GEN3)

Gen3 comprises of smelter-specific software and database technology with management tools to create a comprehensive smelter control and management system.

Contact:

Stephen Flint

Tinnitus and Sound Intensive Video Game

Simple auditory games that are customised to the individual’s condition. The four training applications work to exercise and improve sound categorisation, discrimination and localisation. In the games, correct navigation is directed through auditory cues – responding to “good” sounds is positively rewarded, and responding to “bad” sounds is negatively rewarded. The listening tasks become progressively harder as the game continues. Over time, players are trained to not hear their tinnitus. Initial tests have shown significant auditory improvement

Contact:

Kent Lee

Psychoacoustic technology for hearing loss

Development of a demonstrable technology which compensates excessive frequency masking in hearing loss to improve and speech intelligibility in a crowded room and enhance vocal clarity in musical entertainment

Contact:

Kent Lee

Length sensor based on light absorption at multiple wavelengths

The length sensor is based on light absorption/scattering in a waveguide. Using low cost and stretchable waveguides, the length sensor is able to measure stretches of over 5 times the original length. Simple customisations to the waveguide and light source/detector selection allow for a multitude of different design options for different applications.

Contact:

Joe Rouse

Antimicrobial Aniline Copolymers

Aniline copolymers and the synthesis thereof for use as antimicrobial (antibacterial, antifungal or antiviral material) material of for the manufacture of antimicrobial objects, suitable for use in the health, food, packaging, water, paint, wood, textile, poultry, glass, paper, rubber, ceramic, seafood, sports, plastic and agricultural industries.

Contact:

Stephen Flint

Microactuators for rotary motors

The technology enables thin dielectric elastomer “artificial muscles” with no metallic parts to move in sequence to turn an axle or gear, creating light, efficient motors fractions of a millimetre thick. The motors are flexible with built-in shock absorbancy. Containing no magnetic parts, they are ideal for use in high magnetic fields such as MRI machines, or corrosive environments such as salt water. 

Contact:

Stephen Flint

DE Switches

Development of adapted printing and 3D printing methodologies to exploit new and patented IP for DE Switching (DES), which enables fully-flexible electronic devices (oscillators, logic circuits, others) with all components built using DE processes, leading to soft actuators, simple robots, peristaltic pumps and other devices that operate without conventional electronic controls.

Contact:

Stephen Flint

Fire-retardant Polypropylene

A non-halogenated fire retardant polypropylene (NH-FRPP) developed through an innovative new process to obtain UL 94-V-0 fire rating without any detrimental effect on mechanical properties.

Contact:

Stephen Flint

Optrode

An all-fibre spectroscopic fluorescence bacterial detection system that requires minimal manual intervention, and can give accurate results on site within 30 minutes. Results can show a quantification of bacterial load, live dead ratios for use in antibiotic resistance tests and in the future, species identification.

Contact:

Stephen Flint

Geometric Dielectric Elastomer Switch (GDES)

Development of geometric switching using silicone (or other polymer material) composites containing conductive fillers. Further developments have led to an electrode design of additional novelty, which extends the range of performances offered by said switches, offering wider industrial utility.

Contact:

Stephen Flint

Oxidation Membrane

Smart functionalised membranes that enable the removal of dilute pollutants, especially compounds of emerging concern (such as BPA, EE2, and pesticides) from drinking water. The process involves catalytic oxidation without contamination of the bulk water by excess oxidant or catalyst.

Contact:

Stephen Flint

Mass Spectrometer - Portable dynamic time-of-flight

A novel time-of-flight mass spectrometer based on UniServices patented technology which promises to differentiate performance for analysis of high masses, particularly suited for the growing field of proteomics.

Contact:

Stephen Flint

Fluoride-mediated polymerization methods/Materials for gas separation membranes/New PIM Monomers

New polymeric materials for gas separation membranes with intrinsic microporosity, known as PIM polymers, which can be used primarily for (but not limited to) separating carbon dioxide from methane, oxygen from nitrogen.

Contact:

Stephen Flint

Timber Grading System (using Laser Vibrometer)

Utilising laser power to determine the properties of materials such as the ripeness of fruit or the quality of timber no destructively, in-line and in real time.

Contact:

Stephen Flint

Equine embryo-derived stem cells

The use of equine stem cells and derivatives in equine regenerative medicine focusing especially but not exclusively on tendon injury.

Contact:

Kent Lee